Madhukar Pai*, Andrew Ramsay, Richard O’Brien

There is great excitement in the tuberculosis (TB) scientific community over the introduction of new tools into TB control activities. The development of new tools is an important component of the Global Plan to Stop TB and the World Health Organization’s new global Stop TB Strategy [1,2]. Anticipating the introduction of new tools, the Stop TB Partnership has established a Retooling Task Force to develop a framework for engaging policy makers to foster accelerated adoption and implementation of new tools into TB control programs [3].


Molecular surveillance of multidrug-resistant tuberculosis (MDR TB) was implemented in Europe as case reporting in 2005. For all new MDR TB cases detected from January 2003 through June 2007, countries reported case-based epidemiologic data and DNA fingerprint patterns of MDR TB strains when available. International clusters were detected and analyzed. From 2003 through mid-2007 in Europe, 2,494 cases of MDR TB were  reported from 24 European countries. Epidemiologic and molecular data were linked for 593 (39%) cases, and 672 insertion sequence 6110 DNA fingerprint patterns were reported from 19 countries.

Health care for every American may be the current test of the strength of our convictions, as civil rights was in the 1960s.

by Jeanne M. Lambrew, John D. Podesta, and Teresa L. Shaw

ABSTRACT: Some speculate that Americans are neither politically capable of nor morally committed to solving the health system problems. We disagree. We propose a plan that insures all and improves the value and cost-effectiveness of health care by knitting together employer-sponsored insurance and Medicaid; promoting prevention, research, and information technology; and financing its investments through a dedicated value-added tax. By prioritizing practicality, fairness, and responsibility, the plan aims to avoid ideological battles and prevent fear of major change. By emphasizing the moral imperative for change, especially relative to other options on the policy agenda, it aims to create momentum for expanding and improving health coverage for all.

Karen R. Steingart, Nandini Dendukuri, Megan Henry, Ian Schiller, Payam Nahid, Philip C. Hopewell, Andrew Ramsay, Madhukar Pai, and Suman Laal

Received 26 September 2008/Returned for modification 4 November 2008/Accepted 24 November 2008

Serological antibody detection tests for tuberculosis may offer the potential to improve diagnosis. Recent metaanalyses have shown that commercially available tests have variable accuracies and a limited clinical role. We reviewed the immunodiagnostic potential of antigens evaluated in research laboratories (in-house) for the serodiagnosis of pulmonary tuberculosis and conducted a meta-analysis to evaluate the performance of comparable antigens.

K. F. Laserson, N. J. Binkin, L. E. Thorpe, R. Laing, M. F. Iademarco, A. Bloom, T. B. Agerton, L. Nelson, J. P. Cegielski, O. Ferroussier, T. Holtz, E. Vitek, V. Gammino, K. Tan, A. Finlay, P. Dewan, A. Miranda, G. Aquino, K. Weyer, D. N. Sy, A. Vernon, J. Becerra, J. Ershova,§§ C. D. Wells


SETTING: In resource-poor countries, few tuberculosis (TB) program staff at the national, provincial, and even district levels have the basic analytical and epidemiological skills necessary for collecting and analyzing quality data pertaining to national TB control program (NTP) improvements. This includes setting program priorities, operations planning, and implementing and evaluating program activities.

Sobre a REDE-TB

A Rede Brasileira de Pesquisa em Tuberculose (REDE-TB) é uma Organização Não Governamental (ONG) de direito privado sem fins lucrativos, preocupada em auxiliar no desenvolvimento não só de novos medicamentos, novas vacinas, novos testes diagnósticos e novas estratégias de controle de TB, mas também na validação dessas inovações tecnológicas, antes de sua comercialização no país e/ou de sua implementação nos Programa de Controle de TB no País.




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