This Monograph describes the state of art of the immunomodulator P-MAPA, that has been scientifically studied since the 80s by Brazilian, Chilean, European and American scientists.
Its chemical and physical characteristics, biological properties, pre-clinical results and clinical trials results will be detailed and discussed, in order to explore its potential uses as a therapeutic.
As the experiments confirmed, P-MAPA is a immunomodulator, on of a large group of therapeutics chemicals that helps to control the immune system activity improving cytokines production.
Cytokines are small proteins secreted primarily by immune system cells that promote the proliferation and/or differentiation of others cells and play a significant role in the regulation of the extend the immune response.
They are also the first-line of defense against viral agents and are critical for induction of subsequent specific immune responses.
Examples of cytokines include interleukins (IL-2, IL-7, IL-12), the interferons (IFN), hematopoietic colony stimulating factors (GM-CSF) and proinflamatory factors such as tumor necroses factor (TNF).
Such cytokines operate on lymphocytes by stimulating them to proliferate and by this means, boosting a hosts immune response.